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Is de-normalizing tobacco and its industry a winning approach ?
The so-called "denormalization" approach has progressively imposed itself in the field of tobacco control. This strategy is no longer limited to the health and individual implications of smoking...
Ellen de Guiran,
Thomas Daniel,
Marion Catellin,
Loïc Josseran.
September 2022, page 13
Medical management of limb lymphedema
Lymphedema results from impaired lymphatic transport then tissue modifications (adipose deposition, thickening skin) leading to an increased limb volume. Lymphedema management is based on complete...
Stéphane Vignes.
September 2022, page 18
SARS-CoV-2 infection: two and a half years of fighting the pandemic
Karine Lacombe.
September 2022, page 28
Virological aspects, diagnostic tools and variants of SARS-CoV-2
SARS-CoV-2 is an enveloped non-segmented linear single-stranded positive RNA virus. The envelope carries the protein spike (S) which recognizes the ACE2 receptor on the target cell and allows entry...
Marion Helary,
Maud Salmona,
Éve-Marie Walle,
Linda Feghoul,
Nadia Mahjoub,
Nathalie Schnepf,
Sarah Maylin,
Marie-Laure Chaix,
Jérôme Le Goff,
Constance Delaugerre.
September 2022, page 30
Pathogenesis of SARS-CoV-2 infection
COVID-19 follows a rather stereotyped and reproducible course. While the first events are mediated by direct viral toxicity, resolution of the infection relies on a finely tuned immune response. In...
Quentin Richier,
Léo Plaçais.
September 2022, page 37
Medical management of Covid-19, excluding intensive care
Management of Covid-19 is primarily guided by the severity of the respiratory involvement. Covid-19 is mostly asymptomatic or pauci-symptomatic allowing the ambulatory setting associated with...
Clément Javaux,
Florence Ader.
September 2022, page 41
Management of critical Covid-19 in the intensive care unit
The management of patients with severe to critical forms of Covid-19 in the intensive care unit includes oxygen therapy to treat the deep hypoxaemia induced by the disease, either delivered...
Yoann Elmaleh,
Marc Garnier.
September 2022, page 48
Anti-SARS-CoV-2 vaccination, the Grail ?
The Covid-19 pandemic, which caused an unprecedented health crisis, was partially controlled by the rapid development of effective vaccines against SARS-CoV-2. To date, 5 vaccines are approved in...
Liem Binh Luong Nguyen,
Marie Lachâtre,
Odile Launay.
September 2022, page 55
Covid-19: a lost epidemiological bet ?
For the last two years, the world has been sailing from one epidemic wave to another. From lockdowns to curfews, strategies have changed over time, whether on travel restrictions, mask...
Pascal Crépey,
Clément Massonnaud.
September 2022, page 61
SARS-CoV-2 infection: 10 key messages
Karine Lacombe.
September 2022, page 64
Incontinentia pigmenti: a disease that takes shape on the skin
Soraya Aouali,
Sara Bensalem,
Nada Zizi,
Siham Dikhaye.
September 2022, page 67
Contact dermatitis due to tattoo ink
Sara Bouabdella,
Nada Zizi,
Siham Dikhaye.
September 2022, page 68
Neck pain revealing spontaneous pneumomediastinum
Lorraine Mabon,
Yannick Auffret.
September 2022, page 69
Splenic tuberculosis
Mehdi El Aissate,
Yassine Ennaboulsi,
Salah Eddine El Khade,
Ali Zinebi,
Mohammed Karim Moudden.
September 2022, page 70
Aleukemic cutaneous leukemia
Lamiae Araqi Houssaini,
Fouzia Hali,
Soumiya Chiheb.
September 2022, page 73
Epiploic Fringe Torsion
Henri Gachies,
Rémi Estellé,
Vincent Pérot,
Pierre Mesthé.
September 2022, page 74
Palpebral tuberculosis
Sara Bouabdella,
Hasnau Saddouk,
Nada Zizi,
Siham Dikhaye.
September 2022, page 75
Varicocele, spermatic vein thrombosis and nutcracker syndrome
Fatima Zohra Ahsayen,
Hajar Mahjouba,
Imane Kamaoui,
Imane Skiker.
September 2022, page 76
Metastatic immature mediastinal teratoma
El Mehdi Boudhar,
Abdelhafid Guich,
Youssef Jebbouri,
Hajar Sahimi,
Hasna Hassikou.
September 2022, page 77
Adrenal incidentalomas, most often benign
Adrenal incidentalomas are benign in their great majority, do not evolve towards malignity and do not secrete excess hormones. A dedicated CT scan without injection of contrast medium is the...
Antoine Tabarin.
September 2022, page 81
Sleep in times of pandemic: lessons for the management of insomnia
Sleep is both a determinant of health and a valuable indicator of psychological impact in both personal and global crisis situations. Results from the COCONEL (Coronavirus, Containment Longitudinal...
Damien Léger,
Jonathan Taieb,
Victor Pitron,
Lucie Griffon,
François Beck.
September 2022, page 87
Exanthema and erythroderma in adults and children - Part 2. In children
Lucille Vitek,
Sébastien Barbarot.
September 2022, page 95
Endocrine disruptors: a discussed risk
Catherine Hill,
Robert Barouki,
Karine Audouze,
Xavier Coumoul.
March 2022, page 6
Light pollution
Artificial light can be a polluting agent deleterious for the retina, in relation to the toxicity of the blue band (380-500 nm) of the visible spectrum (380-700nm) specifically used in...
Jean-Louis Dufier,
Yvan Touitou.
March 2022, page 10
Epidemiology, risk factors and current screening in rectal cancer
Incidence and survival data from the Francim Cancer Registry Network allowed an estimate of the national incidence of rectal cancer and its prognosis up to 20 years after diagnosis. In 2018, 13 744...
Anne-Marie Bouvier,
Sylvain Manfredi.
March 2022, page 18
Initial staging of rectal cancer
Rectal cancers are one of the most frequent digestive cancers. Most of them are diagnosed during organized cancer screening or based on evocative symptoms. After a thorough clinical examination...
Ingrid Faouzi,
Olivier Lucidarme.
March 2022, page 25
Contribution of neoadjuvant chemotherapy in rectal cancer
In patients with locally advanced rectal cancer, preoperative radiotherapy and complete mesorectal excision have reduced the risk of locoregional recurrence. However, these treatments have not...
Jean-Baptiste Bachet.
March 2022, page 31
Rectal cancer: Is the era for de-escalation arrived ?
The reference treatment of rectal cancer relies on carcinologic resection including total mesorectal excision. In patients with locally advanced rectal cancer (cT3T4 and/or cN+), preoperative...
Antoine Brouquet.
March 2022, page 39
Rectal cancers resected for cure: monitoring, secondary prevention and late complications
Colorectal cancer incidence has increased by more than 50 % over the past 30 years. Over the same period, the number of deaths has remained stable, reflecting major therapeutic advances. The 5-year...
Côme Lepage.
March 2022, page 44
Rectal cancer: 10 key messages
Jean-Baptiste Bachet.
March 2022, page 51
Botryomycoma
Rim Ouadji,
Siham Nasri,
Soumaya Nasri,
Imane Kamaoui,
Imane Skiker.
March 2022, page 54
A rare cause of ischemic stroke: Lyme disease
Chantal Antoine,
Melody Amouyel.
March 2022, page 55
Extended Favre-Racouchot disease
Hasnae Saddouk,
Hanan Ragragui,
Afaf Khouna,
Siham Dikhaye,
Nada Zizi.
March 2022, page 58
Methanol poisoning
Siham Nasri,
Widad Abbou,
Imane Kamaoui,
Imane Skiker.
March 2022, page 59
Gluten intolerance in infants and children: diagnosis and what recommendations
Gluten intolerance or celiac disease is a relatively common pathology that is still underdiagnosed in pediatrics due to its heterogeneous presentation. Apart from the classic form of malabsorption...
Julie Lemale.
March 2022, page 60
Update on bowel endometriosis
Endometriosis is a relatively common female disease with increasing incidence, probably because of better diagnostic tools and a better understanding of the pathology. We will focus our subject on...
Laetitia Mais.
March 2022, page 65
Abnormal movements
Matthieu Bereau,
Christine Tranchant.
March 2022, page 71
Eosinophilia
Achille Aouba,
Samuel Deshayes.
March 2022, page 79
New glaucoma surgery procedures
The treatment of glaucoma aims to lower intraocular pressure in order to stop the evolution of the optic neuropathy. Surgery is indicated if medical and/or laser treatments are not sufficient...
Florent Aptel.
December 2021, page 6
Impact of prevention and treatment strategies on the epidemiology of HIV infection in France and around the world
The UNAIDS goals will not be achieved in 2030 without a global effort specifically focused on HIV prevention. Many tools are available, named as diversified prevention, adapted to each individual,...
Laurence Slama.
December 2021, page 12
PrEP for HIV prevention, major tool of the global diversified prevention strategy
Laurence Slama.
December 2021, page 19
Mother-to-child transmission of HIV: a success of prevention
Jeanne Sibiude.
December 2021, page 22
Long-term follow-up of persons living with HIV
Life expectancy of persons living with HIV is reaching that of the general population. In consequence they are exposed to age-related comorbidities and complications, with both classical and HIV-...
Jean-Paul Viard.
December 2021, page 25
Excessive weight gain in persons treated for HIV: an adverse effet of integrase inhibitors and «TAF» ?
Jean-Paul Viard.
December 2021, page 32
The future of persons born with HIV
Jean-Paul Viard.
December 2021, page 34
Current treatment of HIV infection
Thirty-five years have passed since the first cases of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). The HIV infection has become a chronic viral infection, with the...
Romain Palich.
December 2021, page 36
Primary HIV infection: a therapeutic emergency
Romain Palich.
December 2021, page 44
HIV infection: 10 key messages
Jean-Paul Viard.
December 2021, page 47
Cerebral cavernoma
Christine Kora,
Soumia El Arabi,
Widad Abbou,
Imane Skiker.
December 2021, page 50
Hughes-Stovin syndrome and Behçet disease
Sara Aouame,
Mehdi Badidi.
December 2021, page 51
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