Result : 34

Primary biliary cholangitis

Primary biliary cholangitis (formally primary biliary cirrhosis, PBC) is the most common chronic cholestatic liver disease in humans. It is a presumed autoimmune liver disease, characterized by...
 Pierre-Antoine Soret, Olivier Chazouillères, Christophe Corpechot. November 2021, page 45

Hypercoagulability in cancer

Gilles Pernod. May 2022, page 18

Prevention of venous thromboembolism in patients with cancer

Risk of venous thromboembolism (VTE) is elevated in cancer and leads to high morbidity and mortality in this population. Drug prophylaxis is questionable, due hemorrhagic risk in these patients,...
 Florence Parent, Mariana Preda, Andrei Seferian. May 2022, page 30

Internal jugular vein thrombosis and esophageal adenocarcinoma

 Landry Darley, Clément Drouet, Alexandre Cochet. May 2022, page 45

Eosinophilia

 Achille Aouba, Samuel Deshayes. March 2022, page 79

New glaucoma surgery procedures

The treatment of glaucoma aims to lower intraocular pressure in order to stop the evolution of the optic neuropathy. Surgery is indicated if medical and/or laser treatments are not sufficient...
 Florent Aptel. December 2021, page 6

PrEP for HIV prevention, major tool of the global diversified prevention strategy

 Laurence Slama. December 2021, page 19

Main acute poisonings: analgesics

 Nicolas Franchitto. December 2021, page 59

Diagnostic strategy for intrauterine lesions

The diagnostic strategy for intrauterine lesions is a question that arises very frequently in gynecological consultations. Endometrial cancer is more frequent in postmenopausal women and bleeding...
 Jérémie Belghiti, Sophie Egels, Geoffroy Canlorbe. December 2022, page 22

Ophthalmic shingles in an immunocompetent child

 Hanan Ragragui Ouasmin, Youssef Almheirat, Hasnae Saddouk, Siham Dikhaye, Nada Zizi. December 2022, page 51

Split hand sign in Charcot's disease

 Christian Brosset, Linh H Nguyen, François Pruvot, Anh Giang Thuc, Hien Q Nguyen. December 2022, page 52

Infant gastroesophageal reflux disease: physiological or pathological?

Gastroesophageal reflux (GER) is defined by the rise of gastric contents into the esophagus, with or without externalization. GER is very common in young infants, with a peak around 4 months, and...
 Aurélie Bourchany, Emmanuel Mas. December 2022, page 74

Epidemiology and risk factors of cancers of the upper aero-digestive tract

With more than 18.000 cases annually, head and neck cancers rank 5th among the most common cancers in France. In 90% of cases, it is squamous cell carcinoma. It reaches the oral cavity in 25%, 15%...
 Nicolas Le Clerc. March 2023, page 18

HPV vaccination and prevention of oropharyngeal cancers

Anti-HPV vaccination was proposed in France from 2006 to prevent anogenital cancers, and in particular cancer of the cervix. This vaccination was mainly offered to young girls. However, HPV-induced...
 Erwan de Mones Del Pujol. March 2023, page 21

Cancers of the upper aerodigestive tract: the particular case of nasopharyngeal cancer

Nasopharyngeal carcinomas belong –in France- to the spectrum of rare diseases with several specificities owing to their etiology, epidemiology, diagnosis and therapeutics compared with other head...
 François-Régis Ferrand, Pierre Busson. March 2023, page 45

The history of Hodgkin lymphoma

Hodgkin lymphoma was initially considered to be caused by infectious agents. The Hodgkin and Reed-Sternberg tumor cells are derived from mature B cells and transforming events were identified....
 Christophe Fermé. September 2023, page 21

Positron emission tomography: a central role in assessment and evaluation

 Salim Kanoun. September 2023, page 35

Living with… amyotrophic lateral

 Claude Desnuelle. September 2023, page 78

Epidemiology and pathophysiology of giant cell arteritis

Giant cell arteritis (GCA) is a granulomatous vasculitis. It affects patients over 50 years of age, predominantly women. The pathophysiology of GCA involves genetic and environmental factors...
 Hélène Greigert, Bernard Bonnotte, Maxime Samson. June 2023, page 39

Spontaneous pneumomediastinum

 Anne Le Coat, Victor Hurpin, Ophélie Pignon, Xavier Fouilland. December 2023, page 80

Pathophysiological hypothesis and diagnosis of insomnia disorder

All pathophysiological models place hyperarousal as a central process in the mechanisms of insomnia. These models differ, however, in terms of the importance and role of the variables explaining...
 Jean-Arthur Micoulaud-Franchi, Julien Coelho, Léa Boileau, Clélia Quiles, Pierre-Alexis Geoffroy. June 2024, page 38

Infectious endocarditis: from epidemiology to prevention

The incidence of infective endocarditis is estimated between 30 and 80 cases per million inhabitants and per year in the general population in industrialized countries. It is heterogeneous and...
 Bernard Iung. October 2024, page 22

Complications of infective endocarditis

The high in-hospital mortality of patients with infective endocarditis (about 20%) is mainly due to its complications. These complications are essentially of cardiac, neurological, and infectious...
 Faouzi Trojette, Chloé Di Lena, Yohann Bohbot, Dan Rusinaru, Christophe Tribouilloy. October 2024, page 43

Major hypereosinophilia associated with Fasciola hepatica distomatosis

 Thierry Carmoi, Magali Billhot, Marc Aletti. October 2024, page 60

Renal colic management

Renal colic is a common reason for consultation or emergency room visit. In most of the cases, it is caused by the migration of a urinary calculus and the resulting ureteral obstruction. In 2022...
 Gauthier Raynal, Christophe Alméras. October 2024, page 80

Bipolar disorder in adolescents and adults

 Christophe Lançon. October 2024, page 87

Bipolar depression, suicide and the prescription of antidepressants

 Christophe Lançon. October 2024, page 94

Phage therapy: where do we stand?

Bacteriophages, discovered at the beginning of the 20th century by Félix d'Hérelle, are viruses that infect and destroy bacteria. Unlike antibiotics, phages are specific to a given bacterial...
 Alexandre Bleibtreu, Sylvain Diamantis. December 2024, page 46

Atypical bacterial pneumonias

Atypical bacterial pneumonias are caused by several pathogens including Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila, Chlamydia psittaci, Coxiella burnetii, and Francisella...
 Romaric Larcher, Paul Loubet. March 2025, page 75

Special features of ANCA-associated vasculitides

Necrotizing vasculitis associated to antineutrophil cytoplasmic antibodies (ANCA) are one of the subgroups of vasculitis affecting small-sized vessels. Fibrinoid necrosis of the vascular wall is...
 Loïc Guillevin. November 2025, page 27

Epidemiology and risk factors of ANCAassociated vasculitides

ANCA-associated vasculitides (AAV) are a group of small-vessel vasculitides including microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA), and eosinophilic granulomatosis with...
 Lucas Pacoureau, Maxime Beydon, Benjamin Terrier, Yann Nguyen. November 2025, page 34

Recent developments in the treatment of ANCA-associated vasculitides

The treatment of antineutrophil cytoplasm antibody-associated (ANCA) vasculitis is based on induction therapy to achieve remission, followed by maintenance therapy to prevent relapse. Management...
 Xavier Puéchal. November 2025, page 43

Towards more targeted therapies in the treatment of ANCA-associated vasculitides

The treatment of ANCA-associated vasculitides (AAV) is based on therapeutic strategies that achieve remission and significantly reduce the risk of relapse in most cases over the medium term....
 Alexandre Karras. November 2025, page 49

ANCA-associated vasculitides: 10 key messages

 Benjamin Terrier. November 2025, page 54