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Alcohol consumption and high blood pressure
Cardiovascular disease is the second leading cause of alcohol-attributable mortality after cancer. The impact of alcohol consumption on blood pressure and the risk of cardiovascular pathologies are...
Mickael Naassila,
Naouras Bouajila,
Daniel Thomas,
Henri-Jean Aubin.
September 2023, page 81
Pain in children. Assessment and analgesic treatments
Anne Defontaine,
Claude Ecoffey.
September 2023, page 98
Biotherapies for the treatment of ulcerative colitis
The treatment of ulcerative colitis has evolved considerably since it must, for most patients, allow healing of inflammatory colonic lesions and no longer a simple remission of clinical symptoms....
Xavier Treton.
June 2023, page 8
Therapeutic advances in HER2+ breast cancer
58,000 new cases of breast cancer occured in France in 2018, of which 15-20% are HER2-positive. HER2-targeted therapies deeply modified the management of these tumors, first by the introduction of...
Marie Alexandre,
William Jacot.
June 2023, page 33
Diagnosis of giant cell arteritis
The diagnosis of giant cell arteritis (GCA) must be made promptly in order to initiate appropriate treatment aimed at relieving symptoms and avoiding ischemic complications, particularly visual...
Hélène Greigert,
Bernard Bonnotte,
Maxime Samson.
June 2023, page 46
Treatment of giant cell arteritis
The treatment of giant cell arteritis (GCA) is based on glucocorticoids. This treatment significantly reduces the risk of ischemic complications, especially those of a visual nature, rapidly...
Maxime Samson,
Hélène Greigert,
Bernard Bonnotte.
June 2023, page 55
Living with… Rendu-Osler disease
Alexandre Guilhem.
June 2023, page 84
Identification of cutaneous adverse drug reactions
Cutaneous adverse drug reactions are common. The most common are maculopapular exanthemas, which heal within a few days. However, clinical and biological signs of severity should be ruled out....
Saskia Ingen-Housz-Oro.
June 2023, page 87
Biotherapies in severe childhood asthma
Asthma is a chronic inflammatory disease of the lower airways and is one of the most common chronic conditions during childhood. The management of severe asthmatic patients must be...
Yanis Bouderbala,
Évangéline Clark,
Marion Tabardel,
Pascal Demoly,
Davide Caimmi.
December 2023, page 6
Salivary gland infections or sialadenitis
Salivary infections, or sialadenitis, affect all types of patients but are most common in elderly or dehydrated patients. Clinical signs include pain, skin erythema, gland oedema, fever and...
Joffrey Molher.
December 2023, page 21
Marshall syndrome
Marshall syndrome also known as PFAPA syndrome belongs to the group of autoinflammatory diseases. The acronym reflects the main clinical features of the disease: periodic fever, aphthous...
Pascal Pillet,
Marion Bailhache.
December 2023, page 41
Hereditary systemic auto-inflammatory diseases associated with cryopyrin
CAPS (cryoprine-associated periodic syndromes) are a group of auto-inflammatory diseases of varying severity, most often beginning very early in life and characterized by febrile episodes, a...
Bénédicte Neven.
December 2023, page 58
Autoinflammatory diseases in children: 10 key messages
Brigitte Bader-Meunier.
December 2023, page 67
Dynamic scapula alata
Audrey Boutrois,
Martin Gry,
Georges Pfister.
December 2023, page 77
Nutrition and nutritional needs of infants and children: a summary
Julie Lemale.
December 2023, page 101
New Alzheimer's drugs: A ray of hope or a new mirage?
Gilles Bouvenot,
Pierre Le Coz.
March 2024, page 8
The choice of a life without children under the influence of societal concerns
Previously unpublished data from 2021 provide an update on the motivations of people who choose not to have children, considering a context of strong social pressure to conceive and a declining...
Charlotte Debest.
March 2024, page 17
Stubborn metatarsalgias
Charlène Fraysse,
Victoria Picquendar,
Caroline Demurger,
Marion Gardies,
Sandrine Vlavonou.
March 2024, page 58
Waardenburg syndrome
Ayoub Boubekri,
Walid Atmani,
Mustapha Bensghir.
March 2024, page 59
Erythrodermic psoriasis
Laurie Rollin,
Noémie Rioual,
Julie Aubret,
Maria Dolghin,
Xavier Fouilland.
March 2024, page 62
Urinary incontinence in children
Urinary incontinence in children and adolescents is most often of functional origin. Questioning and clinical examination with a bladder diary should look for underlying urological or neurological...
Hina Simonnet,
Pauline Lallemant-Dudek.
March 2024, page 76
Advances in antibiotic therapy for tuberculosis
Treatment of tuberculosis is experiencing significant advancements. For the first time, a therapeutic regimen based on rifapentine and moxifloxacin allows for a reduction of treatment duration of...
Thomas Maitre,
Lorenzo Guglielmetti,
Jérôme Robert,
Alexandra Aubry,
Nicolas Veziris.
June 2024, page 8
Feedback on the "Use of the calcium score in daily practice" update
Alexandre Malmartel,
Rémy Boussageon.
June 2024, page 19
Insomnia: definitions, epidemiology and changes with age
Chronic insomnia is a disorder defined as a subjective complaint relating to the quality and/or quantity of sleep associated with daytime impact, and which must be present 3 nights per week for a...
Julie Margrethe Dubois,
Alexandre Rouen,
Damien Léger.
June 2024, page 23
Insomnia and the biological clock
Multiple physiological and biological rhythms known as «circadian» are generated by the biological clock that controls them within the suprachiasmatic nuclei of the hypothalamus. However, the most...
Damien Léger,
Alexandre Rouen,
Marie-Françoise Vecchierini,
Victor Pitron.
June 2024, page 34
Insomnia/sleep apnea: COMISA
Marie-Pia D'Ortho,
Amel Tebal,
Sarah Hartley.
June 2024, page 47
Pharmacotherapies for insomnia
The first line of treatment in adult chronic insomnia is cognitive behavioral therapy (CBT). However, its difficult accessibility limited its use and medications are still often prescribed....
Marie-Françoise Vecchierini,
Damien Léger.
June 2024, page 63
Nausea and vomiting in pregnancy
Nausea and vomiting during pregnancy are common symptoms experienced by pregnant women. In more severe cases, known as hyperemesis gravidarum, these symptoms can become a pathological condition...
Philippe Deruelle,
Loïc Sentilhes,
Louise Ghesquière,
Raoul Desbrière,
Guillaume Ducarme,
Luisa Attali,
Annic Jarnoux,
France Artzner,
Audrey Tranchant,
Thomas Schmitz,
Marie-Victoire Sénat.
June 2024, page 86
What are the indications for corticosteroid therapy in COPD?
In stable state chronic obstructive pulmonary disease (COPD), inhaled corticosteroids (ICS) should be used in case of frequent exacerbation only, associated with long-term bronchodilators including...
Gaëtan Deslée.
June 2024, page 100
Health effects of alcohol: untangling the truth from the false!
Daily alcohol consumption is associated with an increased risk of death, even at low doses. However, it remains high in France, where a large proportion of the population consumes alcohol in excess...
Catherine Hill.
October 2024, page 6
When should short-term antibiotic therapy be chosen?
Reducing antibiotic exposure by shortening treatment duration is a public health priority that could mitigate the emergence of bacterial resistance, minimize adverse effects, and lower costs....
Emma D'Anglejan,
Frédérique Bouchand,
Aurélien Dinh.
October 2024, page 14
Infectious endocarditis: strategy for diagnosis
The diagnosis of infective endocarditis is often difficult because the clinical presentations are very heterogeneous. Epidemiology has evolved with more acute forms, different microorganisms, and...
Anne Bernard,
Nicolas Chane-Sone,
Fanny Dion,
Adrien Lemaignen.
October 2024, page 27
Mask tackle in apnea
Guillaume Janet-Maitre,
Arnaud Druelle.
October 2024, page 59
Sargassum seaweed assaults the French West Indies
Since 2011, Martinique and the islands of Guadeloupe have been affected by repeated groundings, culminating in an exceptional wave in 2018. While the sargassum ( Sargassum natans and S. fluitans )...
Dabor Resiere,
Jonathan Florentin,
Rémi Nevière.
October 2024, page 71
Bipolar depression, suicide and the prescription of antidepressants
Christophe Lançon.
October 2024, page 94
Medical anthropology: the contribution of Éric de Rosny, "the African Jesuit"
Jacqueline Faure,
Adrienne Lerner.
October 2024, page 95
Antimicrobial resistance in human and veterinary medicine: where are we?
In both human and veterinary medicine, the evolution of antimicrobial resistance is worrying for some antibiotics or bacterial species, but less for others. In humans and animals, the picture for...
Laurence Armand-Lefèvre,
Jean-Yves Madec.
December 2024, page 14
Risk of acquiring antibiotic-resistant bacteria and travel
The continuing expansion of international tourism increases the opportunities of contact with diverse epidemiological environments, leading to both a risk of bacterial acquisition or infection for...
Paul-Henri Consigny,
Laurence Armand-Lefèvre.
December 2024, page 20
Shortened antimicrobial therapy duration
Antibiotic treatment durations represent an important field of current clinical research. Indeed, shortening antibiotic duration during bacterial pathologies has several advantages: reducing the...
Aurélien Dinh,
Bernard Castan.
December 2024, page 26
Hospital antimicrobial stewardship
Hospital antimicrobial stewardship programs have been thought to preserve the efficacy of antimicrobials for the treatment of human and animal bacterial infections. They must apply for every...
Philippe Lesprit,
Patricia Pavese.
December 2024, page 34
How to read new antimicrobial susceptibility testing results?
Antimicrobial susceptibility testing (AST) results (formerly 'susceptible', 'intermediate' and 'resistant') are now expressed with the new susceptibility categories 'susceptible, standard dosing...
Frédéric Schramm,
Raphaël Lepeule.
December 2024, page 40
Phage therapy: where do we stand?
Bacteriophages, discovered at the beginning of the 20th century by Félix d'Hérelle, are viruses that infect and destroy bacteria. Unlike antibiotics, phages are specific to a given bacterial...
Alexandre Bleibtreu,
Sylvain Diamantis.
December 2024, page 46
New challenge in antibacterial treatments: 10 key messages
Pierre Tattevin.
December 2024, page 51
Aortomesenteric clamp syndrome
Amine Bentahar,
Aymen El Farouki,
Khalid Gharbi,
Mohammed Essarghini.
December 2024, page 55
Intracardiac thrombosis, a rare complication of Behçet's disease
Yassine Ennaboulsi,
Mehdi El Aissate,
Salah Eddine El Khader,
Mohammed Karim Moudden,
Ali Zinebi.
December 2024, page 59
Living with… an obsessivecompulsive disorder
Alexandre Connor.
December 2024, page 62
Fractures in children: epidemiological, diagnostic and therapeutic features
Mathilde Gaume,
Clélia Thouement,
Raphaël Vialle,
Manon Bachy-Razzouk.
December 2024, page 75
Juvenile idiopathic arthritis: outcome in adulthood?
On average, 40% of juvenile idopathic arthritis remain active in adulthood, with differences according to the type (oligoarticular, polyarticular, enthesitis related arthiritis). It is essential to...
Chantal Deslandre.
March 2025, page 49
Claude-Bernard-Horner syndrome
Chiara Aicardi,
Ulysse Comte,
Alexis Petit,
Audrey Oulagir.
March 2025, page 57
Zinner syndrome
Zakaria Haddadi,
Siham Bhallil,
Siham Nasri,
Imane Kamaoui,
Imane Skiker.
March 2025, page 58
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