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Long-term follow-up of persons living with HIV
Life expectancy of persons living with HIV is reaching that of the general population. In consequence they are exposed to age-related comorbidities and complications, with both classical and HIV-...
Jean-Paul Viard.
December 2021, page 25
Cerebral cavernoma
Christine Kora,
Soumia El Arabi,
Widad Abbou,
Imane Skiker.
December 2021, page 50
Hughes-Stovin syndrome and Behçet disease
Sara Aouame,
Mehdi Badidi.
December 2021, page 51
Practice guide for the management of nightmare disorders
Nightmares are a common parasomnia that occurs mainly during REM sleep (paradoxical sleep) and at all ages. Recurrent nightmares, also known as nightmare disorder, are considered a clinical entity...
Agnès Brion.
December 2021, page 52
Clostridioides difficile: updated recommendations
Clostridioides difficile is a spore-forming anaerobic enteropathogen responsible for a wide spectrum of clinical features ranging from mild uncomplicated diarrhoea to severe debilitating disease,...
Frédéric Barbut,
Catherine Eckert,
Valérie Lalande,
Killian Le Neindre,
Jeanne Couturier.
December 2022, page 6
End of life: we must distinguish between euthanasia and assisted suicide
Pierre Le Coz.
December 2022, page 18
Diagnostic strategy for intrauterine lesions
The diagnostic strategy for intrauterine lesions is a question that arises very frequently in gynecological consultations. Endometrial cancer is more frequent in postmenopausal women and bleeding...
Jérémie Belghiti,
Sophie Egels,
Geoffroy Canlorbe.
December 2022, page 22
Microsatellite instability in endometrial cancer
The microsatellite instability reflects genetic instability that can be sought in tumors, using two methods, immunohistochemistry and molecular biology. Currently in France, a systematic evaluation...
Justine Varinot.
December 2022, page 30
Evolution of endometrial cancer surgery
Minimally invasive surgery (laparoscopic or robotic assisted) is currently recommended when surgery is envisaged, including for patients in the high risk group. The place of the uterine manipulator...
Geoffroy Canlorbe,
Marianne Nikpayam,
Jérémie Belghiti.
December 2022, page 35
Adjuvant treatments for endometrial cancer
Primary treatment for endometrial carcinoma is surgical. Adjuvant treatment is based on risk profile according to histological type, grade, lymphovascular involvement, FIGO stage and genomic...
Nicolas Meillan.
December 2022, page 41
Conservative treatments for endometrial cancer
Treatment for early endometrial cancer remains based on hysterectomy. However, in patients of reproductive age with a pregnancy desire, conservative alternative may be considered in case of...
Maha Eid,
Clémentine Gonthier,
Margot Bucau,
Martin Koskas.
December 2022, page 45
Ophthalmic shingles in an immunocompetent child
Hanan Ragragui Ouasmin,
Youssef Almheirat,
Hasnae Saddouk,
Siham Dikhaye,
Nada Zizi.
December 2022, page 51
Split hand sign in Charcot's disease
Christian Brosset,
Linh H Nguyen,
François Pruvot,
Anh Giang Thuc,
Hien Q Nguyen.
December 2022, page 52
Cranial involvement in Paget's disease
Ahmed Mougui,
Imane El Bouchti.
December 2022, page 53
Reversible cerebral vasoconstriction syndrome
Guillaume Delannoy,
Sébastien Gazzola.
December 2022, page 56
Vesiculo-pustular rash diffuse monomorphic
Hanane Daflaoui,
Hasna Saddouk,
Youssef Joudeh,
Siham Dikhaye,
Nada Zizi.
December 2022, page 59
Infant gastroesophageal reflux disease: physiological or pathological?
Gastroesophageal reflux (GER) is defined by the rise of gastric contents into the esophagus, with or without externalization. GER is very common in young infants, with a peak around 4 months, and...
Aurélie Bourchany,
Emmanuel Mas.
December 2022, page 74
To know the main occupational risks for maternity, related to the mother's work
Philippe Deruelle,
Florent Fuchs,
Noémie Ranisavljevic,
Martha Duraes.
December 2022, page 85
A history of women physicians (part one)
Jean-Noël Fabiani-Salmon.
December 2022, page 101
A history of women physicians (part two)
Jean-Noël Fabiani-Salmon.
December 2022, page 105
Therapeutic revolutions against melanoma
Responsible for 90% of skin cancer deaths, melanoma is the most aggressive skin tumor. Although the main risk factor is known, its incidence doubles every 10 years. Actually, intense and repeated...
Mathilde Amiot,
Céleste Lebbé.
March 2023, page 6
Epidemiology and risk factors of cancers of the upper aero-digestive tract
With more than 18.000 cases annually, head and neck cancers rank 5th among the most common cancers in France. In 90% of cases, it is squamous cell carcinoma. It reaches the oral cavity in 25%, 15%...
Nicolas Le Clerc.
March 2023, page 18
Imaging assessment and diagnostic guidance of upper aerodigestive tract cancers
The upper aerodigestive tract (UADT) has a complex anatomical architecture, which is only partially accessible by clinical examination and for which a detailed imaging analysis is necessary to...
Anne-Laure Gaultier,
Guillaume Reverdito,
Aurélien Saltel-Fulero.
March 2023, page 24
Therapeutic strategies for upper aerodigestive tract cancers
Upper aerodigestive tract squamous cell carcinomas are the most frequent head and neck cancers. They are generally associated with alcohol and tobacco, but can also be HPV-induced for the...
Julia Fanchette,
Caroline Halimi.
March 2023, page 31
Is surgery for ENT cancers less mutilating than in the past ?
Nicolas Le Clerc.
March 2023, page 38
Surveillance after cancer of the upper aerodigestive tract
Gérald Bonardel,
Nicolas Le Clerc.
March 2023, page 40
Cancers of the upper aerodigestive tract: the particular case of nasopharyngeal cancer
Nasopharyngeal carcinomas belong –in France- to the spectrum of rare diseases with several specificities owing to their etiology, epidemiology, diagnosis and therapeutics compared with other head...
François-Régis Ferrand,
Pierre Busson.
March 2023, page 45
Cancers of the upper aerodigestive tract: 10 key messages
Nicolas Le Clerc.
March 2023, page 52
Oral manifestations of secondary syphilis
Claire Lutz,
Anne-Laure Ejeil.
March 2023, page 55
Cystic retroperitoneal paraganglioma
Hajar Abdelouahab,
Salma Lokman,
Soumia El Arabi,
Ihssane Afilal,
Imane Kamaoui.
March 2023, page 58
First malaria vaccine recommended by WHO
RST,S/AS01, the first WHO recommended vaccine against malaria, is the result of decades of research. It is a recombinant protein vaccine which induces a protection against Plasmodium falciparum...
Wendé-Waoga Guillaume Zango,
Marie-Fleur Durieux,
Jean-François Faucher.
March 2023, page 71
Addiction to cannabis, cocaine, amphetamines, opiates, synthetic drugs
Laurent Karila,
Amine Benyamina.
March 2023, page 85
Opioid substitution therapy and harm reduction
Laurent Karila,
Amine Benyamina.
March 2023, page 94
Representations of death and relationship to death. Anthropological and psycho-existential approaches
Gilles Moutot,
Delphine Peyrat-Apicella,
Guillaume Grandazzi,
Guillaume Robert.
March 2023, page 96
Analyze and use the results of clinical studies in the perspective of good use. Critical analysis, clinical research and levels of evidence
Antoine Pariente,
Sibylle de Germay.
March 2023, page 103
The history of the Reichsuniversität Straßburg revealed
Christian Bonah,
Loïc Lutz.
March 2023, page 118
Retirement age choice and social justice
Joël Ménard.
June 2023, page 17
Therapeutic advances in HER2+ breast cancer
58,000 new cases of breast cancer occured in France in 2018, of which 15-20% are HER2-positive. HER2-targeted therapies deeply modified the management of these tumors, first by the introduction of...
Marie Alexandre,
William Jacot.
June 2023, page 33
Diagnosis of giant cell arteritis
The diagnosis of giant cell arteritis (GCA) must be made promptly in order to initiate appropriate treatment aimed at relieving symptoms and avoiding ischemic complications, particularly visual...
Hélène Greigert,
Bernard Bonnotte,
Maxime Samson.
June 2023, page 46
Carcinoma, Non-Small-Cell Lung
Benjamin Teboul,
Étienne Ghrenassia.
June 2023, page 70
Post-zoster segmental abdominal paralysis
Christian Brosset,
Hien Nguyen Quang,
Anh Giang Thuc,
François Pruvot,
Tu Do Van.
June 2023, page 73
Bilateral axillary supernumerary breasts
Kaoutar Sof,
Hasnae Saddouk,
Hanane Daflaoui,
Ghita Cherkaoui,
Ayat Allah Oufkir,
Nada Zizi,
Siham Dikhaye.
June 2023, page 74
Living with… myasthenia
Emmanuelle Salort-Campana.
June 2023, page 80
Living with… Crohn's disease
Stéphane Nahon.
June 2023, page 82
Identification of cutaneous adverse drug reactions
Cutaneous adverse drug reactions are common. The most common are maculopapular exanthemas, which heal within a few days. However, clinical and biological signs of severity should be ruled out....
Saskia Ingen-Housz-Oro.
June 2023, page 87
Exploration and management of thyroid nodules
Most thyroid nodules are benign (95%) and can benefit from clinical and ultrasound monitoring. Cancers (approximately 5% of nodules) could be suspected, particularly in subjects whose neck was...
Hamza Benderradji,
Christine Do Cao,
Miriam Ladsous,
Jean-Louis Wémeau.
June 2023, page 95
Cancer and fertility preservation
The integration of fertility preservation into the treatment pathway is a major issue for quality of life after cancer, particularly for very young children, adolescents and young adults. Responses...
Blandine Courbiere,
Catherine Poirot,
Christine Decanter,
Nathalie Rives,
Éric Huyghe.
June 2023, page 103
Potomania and carbon monoxide poisoning
Frédéric Geibel,
Christine Perret-Guillaulme,
Paul Gérard.
June 2023, page 108
Ambroise Paré, the most famous of the barber-surgeons
Jean-Noël Fabiani-Salmon.
June 2023, page 125
New antibiotics to deal with antibiotic resistance
The current increase in antibiotic resistance exposes to the risk of therapeutic impasse. To deal with this public health problem, developing new antibiotics that are effective (directly or in...
Pauline Huriez,
Benoît Pilmis.
September 2023, page 6
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