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A better understanding of biological mechanisms
Hervé Ghesquières.
September 2023, page 29
Relapse of Hodgkin lymphoma: second and subsequent line treatments
Patients who fail first-line treatment can be cured with salvage chemotherapy followed by intensified therapy and hematopoietic stem cell autotransplantation. This treatment strategy is feasible...
Bénédicte Deau Fischer.
September 2023, page 48
Challenges of long-term follow up for Hodgkin lymphoma survivors
Challenge of Hodgkin lymphoma care is to obtain a high level of curability and minimize acute toxicities and long-term complications of chemotherapy and radiotherapy. A specific long-term...
Hervé Ghesquières.
September 2023, page 53
Toxicity of targeted therapies and immunotherapy with checkpointinhibitors in Hodgkin lymphoma
In patients at increased risk of recurrence or progression after autotransplantation, or in cases of relapse after autotransplantation or after at least two lines of treatment when intensive...
Jean-Marie Michot,
Julien Lazarovici.
September 2023, page 58
Fertility and gonadal disorders in patients with Hodgkin lymphoma
Christine Rousset-Jablonski.
September 2023, page 69
Cedell fracture
Xavier Fouilland,
Cécile Imfeld.
September 2023, page 77
Alcohol consumption and high blood pressure
Cardiovascular disease is the second leading cause of alcohol-attributable mortality after cancer. The impact of alcohol consumption on blood pressure and the risk of cardiovascular pathologies are...
Mickael Naassila,
Naouras Bouajila,
Daniel Thomas,
Henri-Jean Aubin.
September 2023, page 81
Impact of the environment on health. Part 1. Child: the concept of the first 1 000 days
Umberto Simeoni,
Jean-Baptiste Armengaud.
September 2023, page 91
Biotherapies for the treatment of ulcerative colitis
The treatment of ulcerative colitis has evolved considerably since it must, for most patients, allow healing of inflammatory colonic lesions and no longer a simple remission of clinical symptoms....
Xavier Treton.
June 2023, page 8
Social media and teenagers' mental health
Social media are widely used daily especially amongst adolescents. The fast apparition and evolution of these platforms might be difficult to follow. Social Media can expose to risks that it is...
Natalia Robert,
Nathalie Godart.
June 2023, page 22
Epidemiology and pathophysiology of giant cell arteritis
Giant cell arteritis (GCA) is a granulomatous vasculitis. It affects patients over 50 years of age, predominantly women. The pathophysiology of GCA involves genetic and environmental factors...
Hélène Greigert,
Bernard Bonnotte,
Maxime Samson.
June 2023, page 39
Takayasu's arteritis
Takayasu’s arteritis is an inflammatory panarteritis of the large vessels, preferentially affecting the aorta, its main branches, and the pulmonary arteries. Its incidence is estimated at 1.11...
Alexis F Guédon,
Raphaël Bourgade,
Mounia Elhannani,
Claire Toquet,
Olivier Espitia,
Olivier Fain,
Arsène Mekinian.
June 2023, page 60
Vasculitis of large-caliber vessels: 10 key messages
Maxime Samson,
Hélène Greigert,
Bernard Bonnotte.
June 2023, page 67
Carcinoma, Non-Small-Cell Lung
Benjamin Teboul,
Étienne Ghrenassia.
June 2023, page 70
Post-zoster segmental abdominal paralysis
Christian Brosset,
Hien Nguyen Quang,
Anh Giang Thuc,
François Pruvot,
Tu Do Van.
June 2023, page 73
Unilateral edema of the upper limb
Matthieu Bellakehal,
Joris Marti,
Claire Lequesne,
Albane Buan.
June 2023, page 76
Living with… myasthenia
Emmanuelle Salort-Campana.
June 2023, page 80
Identification of cutaneous adverse drug reactions
Cutaneous adverse drug reactions are common. The most common are maculopapular exanthemas, which heal within a few days. However, clinical and biological signs of severity should be ruled out....
Saskia Ingen-Housz-Oro.
June 2023, page 87
Exploration and management of thyroid nodules
Most thyroid nodules are benign (95%) and can benefit from clinical and ultrasound monitoring. Cancers (approximately 5% of nodules) could be suspected, particularly in subjects whose neck was...
Hamza Benderradji,
Christine Do Cao,
Miriam Ladsous,
Jean-Louis Wémeau.
June 2023, page 95
Management of a patient with pre-eclampsie
Elsa Gottardi,
Édouard Lecarpentier.
June 2023, page 118
Biotherapies in severe childhood asthma
Asthma is a chronic inflammatory disease of the lower airways and is one of the most common chronic conditions during childhood. The management of severe asthmatic patients must be...
Yanis Bouderbala,
Évangéline Clark,
Marion Tabardel,
Pascal Demoly,
Davide Caimmi.
December 2023, page 6
Shared decision-making: ethical issues
Shared decision-making is a decision-making model and a model of interaction between healthcare professionals and healthcare users. Putting together medical-scientific data, experience, values and...
François Blot,
Nora Moumjid.
December 2023, page 11
Press review
François Mallordy.
December 2023, page 16
Salivary gland infections or sialadenitis
Salivary infections, or sialadenitis, affect all types of patients but are most common in elderly or dehydrated patients. Clinical signs include pain, skin erythema, gland oedema, fever and...
Joffrey Molher.
December 2023, page 21
Inflammatory diseases of the salivary
Salivary glands can be affected by inflammatory pathologies. They are most often manifested by the occurrence of swelling of the main salivary glands that can be associated with a dryness. Main...
Gaetane Nocturne,
Marjolaine Gosset.
December 2023, page 25
Salivary gland neoplasms
Salivary gland tumors represent a heterogeneous group of lesions, with various anatomical locations. The most frequent site of involvement is the parotid, and the most frequent histology is...
Florian Chatelet.
December 2023, page 29
Lithiasic salivary gland pathologies
Sialolithiasis is the most frequent pathology affecting the salivary glands. Almost 80% of these lithiasis affect the submandibular gland, in the Wharton duct whilst 20% occur in the parotid gland...
Domitille Camous.
December 2023, page 35
Salivary gland pathologies: 10 key messages
Nicolas Le Clerc.
December 2023, page 39
Mevalonate kinase deficiency
Mevalonate kinase deficiency is a rare, autosomal recessive, auto-inflammatory disease, linked to mutations in the gene MVK , resulting in the activation of pyrin inflammasome and hypersecretion of...
Caroline Galeotti.
December 2023, page 53
Hereditary systemic auto-inflammatory diseases associated with cryopyrin
CAPS (cryoprine-associated periodic syndromes) are a group of auto-inflammatory diseases of varying severity, most often beginning very early in life and characterized by febrile episodes, a...
Bénédicte Neven.
December 2023, page 58
Posterior sternoclavicular dislocation
Xavier Fouilland,
Florine Wojcieszak,
Cécile Imfeld,
Anne Le Coat.
December 2023, page 71
Giant cell tumors
El Mehdi Boudhar,
Maria El Mandour,
Mohammed Ennmer,
Hajar Sahimi,
Hasna Hassikou.
December 2023, page 72
Epidermodysplasia verruciformis or tree-man
Sara Bouabdella,
Nada Zizi,
Soraya Aouali,
Siham Dikhaye.
December 2023, page 74
Paranoid personality disorder
The paranoid personality disorder fascinates and worries health professionals, who are sometimes victims of aggressive claims from their patients. Overestimation of oneself, psychorigidity,...
Mathieu Lacambre.
December 2023, page 87
Nutrition and nutritional needs of infants and children: a summary
Julie Lemale.
December 2023, page 101
Bob Marley, a melanoma will have had the skin of a melomaniac
Jérémy Lupu.
December 2023, page 107
The choice of a life without children under the influence of societal concerns
Previously unpublished data from 2021 provide an update on the motivations of people who choose not to have children, considering a context of strong social pressure to conceive and a declining...
Charlotte Debest.
March 2024, page 17
Anatomy of memory
Memory phenomena involve neuron circuits and neurogenesis processes at the microscopic level. Nevertheless, the central role played by some key structures such as the hippocampus and the limbic...
Laurent Tatu.
March 2024, page 25
Neuropsychology of memory
In neuropsychology, memory is shown as a complex function composed of several memory systems. Five memory systems are proposed: working memory (or short term memory), episodic memory, semantic...
Francis Eustache.
March 2024, page 28
Memory diseases
There are many diseases that permanently affect longterm memory and all of them have in common that they permanently and usually bilaterally disrupt specific neural circuits that underlie it. In...
François Sellal,
Cécile Weiss.
March 2024, page 36
Transient amnesias
Fausto Viader.
March 2024, page 41
Dissociative amnesia: A functional amnesia
Catherine Thomas-Antérion.
March 2024, page 44
How to deal with memory complaints
Memory complaint is a common condition in the general population and can indicate normal brain aging as well as incurable neurodegenerative disease or curable disorders. Therefore, the role of any...
Nicolas Villain.
March 2024, page 46
Urinary incontinence in children
Urinary incontinence in children and adolescents is most often of functional origin. Questioning and clinical examination with a bladder diary should look for underlying urological or neurological...
Hina Simonnet,
Pauline Lallemant-Dudek.
March 2024, page 76
Advances in antibiotic therapy for tuberculosis
Treatment of tuberculosis is experiencing significant advancements. For the first time, a therapeutic regimen based on rifapentine and moxifloxacin allows for a reduction of treatment duration of...
Thomas Maitre,
Lorenzo Guglielmetti,
Jérôme Robert,
Alexandra Aubry,
Nicolas Veziris.
June 2024, page 8
Insomnia: definitions, epidemiology and changes with age
Chronic insomnia is a disorder defined as a subjective complaint relating to the quality and/or quantity of sleep associated with daytime impact, and which must be present 3 nights per week for a...
Julie Margrethe Dubois,
Alexandre Rouen,
Damien Léger.
June 2024, page 23
Health consequences of insomnia
Maurice M Ohayon.
June 2024, page 31
Economic impact of insomnia
Damien Léger,
Victor Pitron.
June 2024, page 32
Insomnia and the biological clock
Multiple physiological and biological rhythms known as «circadian» are generated by the biological clock that controls them within the suprachiasmatic nuclei of the hypothalamus. However, the most...
Damien Léger,
Alexandre Rouen,
Marie-Françoise Vecchierini,
Victor Pitron.
June 2024, page 34
Pathophysiological hypothesis and diagnosis of insomnia disorder
All pathophysiological models place hyperarousal as a central process in the mechanisms of insomnia. These models differ, however, in terms of the importance and role of the variables explaining...
Jean-Arthur Micoulaud-Franchi,
Julien Coelho,
Léa Boileau,
Clélia Quiles,
Pierre-Alexis Geoffroy.
June 2024, page 38
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