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Therapeutic revolutions against melanoma
Responsible for 90% of skin cancer deaths, melanoma is the most aggressive skin tumor. Although the main risk factor is known, its incidence doubles every 10 years. Actually, intense and repeated...
Mathilde Amiot,
Céleste Lebbé.
March 2023, page 6
Imaging assessment and diagnostic guidance of upper aerodigestive tract cancers
The upper aerodigestive tract (UADT) has a complex anatomical architecture, which is only partially accessible by clinical examination and for which a detailed imaging analysis is necessary to...
Anne-Laure Gaultier,
Guillaume Reverdito,
Aurélien Saltel-Fulero.
March 2023, page 24
Therapeutic strategies for upper aerodigestive tract cancers
Upper aerodigestive tract squamous cell carcinomas are the most frequent head and neck cancers. They are generally associated with alcohol and tobacco, but can also be HPV-induced for the...
Julia Fanchette,
Caroline Halimi.
March 2023, page 31
Surveillance after cancer of the upper aerodigestive tract
Gérald Bonardel,
Nicolas Le Clerc.
March 2023, page 40
Cancers of the upper aerodigestive tract: the particular case of nasopharyngeal cancer
Nasopharyngeal carcinomas belong –in France- to the spectrum of rare diseases with several specificities owing to their etiology, epidemiology, diagnosis and therapeutics compared with other head...
François-Régis Ferrand,
Pierre Busson.
March 2023, page 45
Bilateral iatrogenic conjunctivo-palpebral Kaposi's disease
Hasnae Saddouk,
Hanan Ragragui,
Imane Ouadi,
Nada Zizi,
Siham Dikhaye.
March 2023, page 56
Cystic retroperitoneal paraganglioma
Hajar Abdelouahab,
Salma Lokman,
Soumia El Arabi,
Ihssane Afilal,
Imane Kamaoui.
March 2023, page 58
Palmoplantar bullous dyshidrosis
Sara Ben Salem,
Sara Bouabdella,
Mounia Benkaraache,
Nada Zizi,
Siham Dikhaye.
March 2023, page 61
Emphysematous pyelonephritis
Salma Lokman,
Hajar Abdelouahab,
Siham Nasri.
March 2023, page 62
Extremity necrosis revealing antiphospholipid syndrome
Sara Bouabdella,
Siham Dikhaye,
Nadia Zizi.
March 2023, page 64
Scurvy mimicking vasculitis
Cécilia Maillet,
Jonathan Wong So,
Yanis Ramdani,
Adrien Bigot,
Nicole Ferreira-Maldent,
Brigitte Chandenier,
François Maillot,
Alexandra Audemard-Verger.
March 2023, page 65
Misleading isorhythmic dissociation
Charlène Fraysse,
Victoria Picquendar,
Marion Gardies,
Livia Mannaion,
Caroline Demurger.
March 2023, page 66
Living with… a lymphoma
Guy Bouguet.
March 2023, page 69
First malaria vaccine recommended by WHO
RST,S/AS01, the first WHO recommended vaccine against malaria, is the result of decades of research. It is a recombinant protein vaccine which induces a protection against Plasmodium falciparum...
Wendé-Waoga Guillaume Zango,
Marie-Fleur Durieux,
Jean-François Faucher.
March 2023, page 71
Neuromyelitis optica
Neuromyelitis optica (NMO) or neuromyelitis optica spectrum disorder (NMOSD) includes different inflammatory conditions of the central nervous system distinct from multiple sclerosis. It is...
Thomas Roux,
Élisabeth Maillart,
Caroline Papeix.
March 2023, page 77
Addiction to cannabis, cocaine, amphetamines, opiates, synthetic drugs
Laurent Karila,
Amine Benyamina.
March 2023, page 85
Opioid substitution therapy and harm reduction
Laurent Karila,
Amine Benyamina.
March 2023, page 94
Representations of death and relationship to death. Anthropological and psycho-existential approaches
Gilles Moutot,
Delphine Peyrat-Apicella,
Guillaume Grandazzi,
Guillaume Robert.
March 2023, page 96
The anthropological rupture linked to the pandemic
Gilles Moutot,
Delphine Peyrat-Apicella,
Guillaume Grandazzi,
Guillaume Robert.
March 2023, page 102
Analyze and use the results of clinical studies in the perspective of good use. Critical analysis, clinical research and levels of evidence
Antoine Pariente,
Sibylle de Germay.
March 2023, page 103
The history of the Reichsuniversität Straßburg revealed
Christian Bonah,
Loïc Lutz.
March 2023, page 118
New antibiotics to deal with antibiotic resistance
The current increase in antibiotic resistance exposes to the risk of therapeutic impasse. To deal with this public health problem, developing new antibiotics that are effective (directly or in...
Pauline Huriez,
Benoît Pilmis.
September 2023, page 6
Evolutions of the "framework of benefits" system
In the field of compliance, the last thirty years have been marked by an evolution of the regulatory framework in order to adapt an anti-corruption system to the whole ecosystem of health...
Marianne Lahana,
Frédéric Glicenstein.
September 2023, page 15
The history of Hodgkin lymphoma
Hodgkin lymphoma was initially considered to be caused by infectious agents. The Hodgkin and Reed-Sternberg tumor cells are derived from mature B cells and transforming events were identified....
Christophe Fermé.
September 2023, page 21
Epidemiology of classical Hodgkin lymphoma
Classical Hodgkin lymphoma is a rare neoplasia but represents one of the most common cancers in adults younger than 40 years old. Epidemiology of Hodgkin lymphoma remains fascinating with specific...
Hervé Ghesquières.
September 2023, page 25
A better understanding of biological mechanisms
Hervé Ghesquières.
September 2023, page 29
Diagnosis and staging of Hodgkin lymphoma
Hodgkin lymphoma (HL) is composed of two distinct disease entities: classical HL (cHL) and nodular lymphocyte predominant HL (NLPHL). NLPHL is a rare entity with a specific therapeutic management....
Hervé Ghesquières.
September 2023, page 31
Positron emission tomography: a central role in assessment and evaluation
Salim Kanoun.
September 2023, page 35
Frontline therapy for classical Hodgkin lymphoma patients
Upfront first-line chemotherapy is indicated for all features of classical Hodgkin's lymphoma, followed by involved node radiotherapy in early stages; the ABVD protocol (doxorubicin (Adriamycin),...
Cédric Rossi,
Olivier Casasnovas.
September 2023, page 39
Relapse of Hodgkin lymphoma: second and subsequent line treatments
Patients who fail first-line treatment can be cured with salvage chemotherapy followed by intensified therapy and hematopoietic stem cell autotransplantation. This treatment strategy is feasible...
Bénédicte Deau Fischer.
September 2023, page 48
Toxicity of targeted therapies and immunotherapy with checkpointinhibitors in Hodgkin lymphoma
In patients at increased risk of recurrence or progression after autotransplantation, or in cases of relapse after autotransplantation or after at least two lines of treatment when intensive...
Jean-Marie Michot,
Julien Lazarovici.
September 2023, page 58
Fertility and gonadal disorders in patients with Hodgkin lymphoma
Christine Rousset-Jablonski.
September 2023, page 69
Ollier disease
Habib Bellamlih,
Oumaima El Bouazzi,
Soufiane Belabbes,
Abdellatif El Haddad,
Brahim Zinoun,
Taoufik Africha.
September 2023, page 76
Cedell fracture
Xavier Fouilland,
Cécile Imfeld.
September 2023, page 77
Alcohol consumption and high blood pressure
Cardiovascular disease is the second leading cause of alcohol-attributable mortality after cancer. The impact of alcohol consumption on blood pressure and the risk of cardiovascular pathologies are...
Mickael Naassila,
Naouras Bouajila,
Daniel Thomas,
Henri-Jean Aubin.
September 2023, page 81
Impact of the environment on health. Part 1. Child: the concept of the first 1 000 days
Umberto Simeoni,
Jean-Baptiste Armengaud.
September 2023, page 91
Biotherapies for the treatment of ulcerative colitis
The treatment of ulcerative colitis has evolved considerably since it must, for most patients, allow healing of inflammatory colonic lesions and no longer a simple remission of clinical symptoms....
Xavier Treton.
June 2023, page 8
Therapeutic advances in HER2+ breast cancer
58,000 new cases of breast cancer occured in France in 2018, of which 15-20% are HER2-positive. HER2-targeted therapies deeply modified the management of these tumors, first by the introduction of...
Marie Alexandre,
William Jacot.
June 2023, page 33
Social media and teenagers' mental health
Social media are widely used daily especially amongst adolescents. The fast apparition and evolution of these platforms might be difficult to follow. Social Media can expose to risks that it is...
Natalia Robert,
Nathalie Godart.
June 2023, page 22
Epidemiology and pathophysiology of giant cell arteritis
Giant cell arteritis (GCA) is a granulomatous vasculitis. It affects patients over 50 years of age, predominantly women. The pathophysiology of GCA involves genetic and environmental factors...
Hélène Greigert,
Bernard Bonnotte,
Maxime Samson.
June 2023, page 39
Diagnosis of giant cell arteritis
The diagnosis of giant cell arteritis (GCA) must be made promptly in order to initiate appropriate treatment aimed at relieving symptoms and avoiding ischemic complications, particularly visual...
Hélène Greigert,
Bernard Bonnotte,
Maxime Samson.
June 2023, page 46
Treatment of giant cell arteritis
The treatment of giant cell arteritis (GCA) is based on glucocorticoids. This treatment significantly reduces the risk of ischemic complications, especially those of a visual nature, rapidly...
Maxime Samson,
Hélène Greigert,
Bernard Bonnotte.
June 2023, page 55
Takayasu's arteritis
Takayasu’s arteritis is an inflammatory panarteritis of the large vessels, preferentially affecting the aorta, its main branches, and the pulmonary arteries. Its incidence is estimated at 1.11...
Alexis F Guédon,
Raphaël Bourgade,
Mounia Elhannani,
Claire Toquet,
Olivier Espitia,
Olivier Fain,
Arsène Mekinian.
June 2023, page 60
Vasculitis of large-caliber vessels: 10 key messages
Maxime Samson,
Hélène Greigert,
Bernard Bonnotte.
June 2023, page 67
Carcinoma, Non-Small-Cell Lung
Benjamin Teboul,
Étienne Ghrenassia.
June 2023, page 70
Post-zoster segmental abdominal paralysis
Christian Brosset,
Hien Nguyen Quang,
Anh Giang Thuc,
François Pruvot,
Tu Do Van.
June 2023, page 73
Bilateral axillary supernumerary breasts
Kaoutar Sof,
Hasnae Saddouk,
Hanane Daflaoui,
Ghita Cherkaoui,
Ayat Allah Oufkir,
Nada Zizi,
Siham Dikhaye.
June 2023, page 74
Unilateral edema of the upper limb
Matthieu Bellakehal,
Joris Marti,
Claire Lequesne,
Albane Buan.
June 2023, page 76
Folliculitis decalvans on a cutis verticis gyrata
Sara Bouabdella,
Soraya Aouali,
Siham Dikhaye,
Nada Zizi.
June 2023, page 79
Exploration and management of thyroid nodules
Most thyroid nodules are benign (95%) and can benefit from clinical and ultrasound monitoring. Cancers (approximately 5% of nodules) could be suspected, particularly in subjects whose neck was...
Hamza Benderradji,
Christine Do Cao,
Miriam Ladsous,
Jean-Louis Wémeau.
June 2023, page 95
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