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Primary biliary cholangitis
Primary biliary cholangitis (formally primary biliary cirrhosis, PBC) is the most common chronic cholestatic liver disease in humans. It is a presumed autoimmune liver disease, characterized by...
Pierre-Antoine Soret,
Olivier Chazouillères,
Christophe Corpechot.
November 2021, page 45
Epidemiology of poisoning in children
Nicolas Franchitto.
November 2021, page 53
Main acute poisonings: general principles of care, illicit and psychotropic substances, cardiotropic and carbon monoxide
Nicolas Franchitto.
November 2021, page 54
Gayet Wernicke encephalopathy
Christine Kora,
Obed Rockson,
Soumia El Arabi,
Imane Skiker.
January 2022, page 43
Borreliosis and relapsing fever
Relapsing fevers borreliosis (RFB) are caused by bacteria of the genus Borrelia, within the spirochete’s family, transmitted to Humans by arthropods (lice Pediculus humanus, soft ticks of the genus...
Alice Raffetin,
Solène Patrat-Delon,
Céline Cazorla,
Pierre Tattevin,
Carole Eldin.
January 2022, page 51
New therapies in multiple myeloma
Multiple myeloma is the second most common hemopathy in Western countries. The development of the therapeutic arsenal has significantly improved patients’ prognosis. In the early 2000s, autograft,...
Anaïs Schavgoulidze,
Aurore Perrot.
September 2022, page 6
Medical management of Covid-19, excluding intensive care
Management of Covid-19 is primarily guided by the severity of the respiratory involvement. Covid-19 is mostly asymptomatic or pauci-symptomatic allowing the ambulatory setting associated with...
Clément Javaux,
Florence Ader.
September 2022, page 41
Management of critical Covid-19 in the intensive care unit
The management of patients with severe to critical forms of Covid-19 in the intensive care unit includes oxygen therapy to treat the deep hypoxaemia induced by the disease, either delivered...
Yoann Elmaleh,
Marc Garnier.
September 2022, page 48
Varicocele, spermatic vein thrombosis and nutcracker syndrome
Fatima Zohra Ahsayen,
Hajar Mahjouba,
Imane Kamaoui,
Imane Skiker.
September 2022, page 76
Adrenal incidentalomas, most often benign
Adrenal incidentalomas are benign in their great majority, do not evolve towards malignity and do not secrete excess hormones. A dedicated CT scan without injection of contrast medium is the...
Antoine Tabarin.
September 2022, page 81
Exanthema and erythroderma in adults and children - Part 2. In children
Lucille Vitek,
Sébastien Barbarot.
September 2022, page 95
Systemic vasculitis
No abstract available
Olivier Fain,
Arsène Mekinian.
May 2022, page 75
Treatment of cancer associated thrombosis
The treatment of cancer-associated venous thromboembolic disease is complex due to an increased risk of thrombotic recurrence and bleeding under treatment. During the first 6 months, low molecular...
Olivier Sanchez.
May 2022, page 21
Prevention of venous thromboembolism in patients with cancer
Risk of venous thromboembolism (VTE) is elevated in cancer and leads to high morbidity and mortality in this population. Drug prophylaxis is questionable, due hemorrhagic risk in these patients,...
Florence Parent,
Mariana Preda,
Andrei Seferian.
May 2022, page 30
Internal jugular vein thrombosis and esophageal adenocarcinoma
Landry Darley,
Clément Drouet,
Alexandre Cochet.
May 2022, page 45
Calcaneal bone cyst
Adrien Verzi,
Julien Samy,
Guillaume Comat,
Guillaume Michoud,
Grégoire Boca,
Kevin Balasoupramanien.
May 2022, page 49
Mental disorders of the elderly
Dr Cyril Hazif-Thomas,
Dr Hugo Lindenbaum.
May 2022, page 57
Heart murmur in children
Dr Sébastien Hascoët,
Pr Philippe Acar,
Dr Clément Karsenty.
May 2022, page 66
The Argan case or the imaginary disease according to Molièreу
Patrick Dandrey.
May 2022, page 88
Contribution of neoadjuvant chemotherapy in rectal cancer
In patients with locally advanced rectal cancer, preoperative radiotherapy and complete mesorectal excision have reduced the risk of locoregional recurrence. However, these treatments have not...
Jean-Baptiste Bachet.
March 2022, page 31
Rectal cancer: Is the era for de-escalation arrived ?
The reference treatment of rectal cancer relies on carcinologic resection including total mesorectal excision. In patients with locally advanced rectal cancer (cT3T4 and/or cN+), preoperative...
Antoine Brouquet.
March 2022, page 39
Gluten intolerance in infants and children: diagnosis and what recommendations
Gluten intolerance or celiac disease is a relatively common pathology that is still underdiagnosed in pediatrics due to its heterogeneous presentation. Apart from the classic form of malabsorption...
Julie Lemale.
March 2022, page 60
Impact of prevention and treatment strategies on the epidemiology of HIV infection in France and around the world
The UNAIDS goals will not be achieved in 2030 without a global effort specifically focused on HIV prevention. Many tools are available, named as diversified prevention, adapted to each individual,...
Laurence Slama.
December 2021, page 12
PrEP for HIV prevention, major tool of the global diversified prevention strategy
Laurence Slama.
December 2021, page 19
Mother-to-child transmission of HIV: a success of prevention
Jeanne Sibiude.
December 2021, page 22
Long-term follow-up of persons living with HIV
Life expectancy of persons living with HIV is reaching that of the general population. In consequence they are exposed to age-related comorbidities and complications, with both classical and HIV-...
Jean-Paul Viard.
December 2021, page 25
Excessive weight gain in persons treated for HIV: an adverse effet of integrase inhibitors and «TAF» ?
Jean-Paul Viard.
December 2021, page 32
The future of persons born with HIV
Jean-Paul Viard.
December 2021, page 34
Current treatment of HIV infection
Thirty-five years have passed since the first cases of human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). The HIV infection has become a chronic viral infection, with the...
Romain Palich.
December 2021, page 36
Primary HIV infection: a therapeutic emergency
Romain Palich.
December 2021, page 44
HIV infection: 10 key messages
Jean-Paul Viard.
December 2021, page 47
Hughes-Stovin syndrome and Behçet disease
Sara Aouame,
Mehdi Badidi.
December 2021, page 51
Practice guide for the management of nightmare disorders
Nightmares are a common parasomnia that occurs mainly during REM sleep (paradoxical sleep) and at all ages. Recurrent nightmares, also known as nightmare disorder, are considered a clinical entity...
Agnès Brion.
December 2021, page 52
Main acute poisonings: analgesics
Nicolas Franchitto.
December 2021, page 59
Clostridioides difficile: updated recommendations
Clostridioides difficile is a spore-forming anaerobic enteropathogen responsible for a wide spectrum of clinical features ranging from mild uncomplicated diarrhoea to severe debilitating disease,...
Frédéric Barbut,
Catherine Eckert,
Valérie Lalande,
Killian Le Neindre,
Jeanne Couturier.
December 2022, page 6
Conservative treatments for endometrial cancer
Treatment for early endometrial cancer remains based on hysterectomy. However, in patients of reproductive age with a pregnancy desire, conservative alternative may be considered in case of...
Maha Eid,
Clémentine Gonthier,
Margot Bucau,
Martin Koskas.
December 2022, page 45
Ophthalmic shingles in an immunocompetent child
Hanan Ragragui Ouasmin,
Youssef Almheirat,
Hasnae Saddouk,
Siham Dikhaye,
Nada Zizi.
December 2022, page 51
Reversible cerebral vasoconstriction syndrome
Guillaume Delannoy,
Sébastien Gazzola.
December 2022, page 56
Infant gastroesophageal reflux disease: physiological or pathological?
Gastroesophageal reflux (GER) is defined by the rise of gastric contents into the esophagus, with or without externalization. GER is very common in young infants, with a peak around 4 months, and...
Aurélie Bourchany,
Emmanuel Mas.
December 2022, page 74
Palmoplantar bullous dyshidrosis
Sara Ben Salem,
Sara Bouabdella,
Mounia Benkaraache,
Nada Zizi,
Siham Dikhaye.
March 2023, page 61
Extremity necrosis revealing antiphospholipid syndrome
Sara Bouabdella,
Siham Dikhaye,
Nadia Zizi.
March 2023, page 64
Scurvy mimicking vasculitis
Cécilia Maillet,
Jonathan Wong So,
Yanis Ramdani,
Adrien Bigot,
Nicole Ferreira-Maldent,
Brigitte Chandenier,
François Maillot,
Alexandra Audemard-Verger.
March 2023, page 65
Addiction to cannabis, cocaine, amphetamines, opiates, synthetic drugs
Laurent Karila,
Amine Benyamina.
March 2023, page 85
New antibiotics to deal with antibiotic resistance
The current increase in antibiotic resistance exposes to the risk of therapeutic impasse. To deal with this public health problem, developing new antibiotics that are effective (directly or in...
Pauline Huriez,
Benoît Pilmis.
September 2023, page 6
Evolutions of the "framework of benefits" system
In the field of compliance, the last thirty years have been marked by an evolution of the regulatory framework in order to adapt an anti-corruption system to the whole ecosystem of health...
Marianne Lahana,
Frédéric Glicenstein.
September 2023, page 15
A better understanding of biological mechanisms
Hervé Ghesquières.
September 2023, page 29
Frontline therapy for classical Hodgkin lymphoma patients
Upfront first-line chemotherapy is indicated for all features of classical Hodgkin's lymphoma, followed by involved node radiotherapy in early stages; the ABVD protocol (doxorubicin (Adriamycin),...
Cédric Rossi,
Olivier Casasnovas.
September 2023, page 39
Relapse of Hodgkin lymphoma: second and subsequent line treatments
Patients who fail first-line treatment can be cured with salvage chemotherapy followed by intensified therapy and hematopoietic stem cell autotransplantation. This treatment strategy is feasible...
Bénédicte Deau Fischer.
September 2023, page 48
Toxicity of targeted therapies and immunotherapy with checkpointinhibitors in Hodgkin lymphoma
In patients at increased risk of recurrence or progression after autotransplantation, or in cases of relapse after autotransplantation or after at least two lines of treatment when intensive...
Jean-Marie Michot,
Julien Lazarovici.
September 2023, page 58
Ollier disease
Habib Bellamlih,
Oumaima El Bouazzi,
Soufiane Belabbes,
Abdellatif El Haddad,
Brahim Zinoun,
Taoufik Africha.
September 2023, page 76
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